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Ipamorelin

Ipamorelin

08
Selective GH secretagogue · Clean physiological pulse
99% Purity Growth Hormone Clean Profile

Ipamorelin is a GH secretagogue pentapeptide considered the most selective and 'cleanest' of its class. Unlike GHRP-6 or GHRP-2, it does not cause a notable rise in cortisol, prolactin or appetite, making it the preferred option for anti-aging, fat-loss and recovery protocols without hormonal side effects. It generates a physiological GH pulse similar to the natural one, ideal for prolonged use.

Key Benefits
Releases GH without affecting cortisol
Improves body composition
Reduces fat without losing muscle
Optimizes deep sleep
Post-workout recovery
Anti-aging effect
Mechanism of Action
Ipamorelin acts as a selective GH secretagogue, binding to the ghrelin receptor to stimulate a physiological GH pulse similar to the natural one without notably affecting cortisol, prolactin or appetite. This selectivity makes it ideal for prolonged use in anti-aging, fat-loss and recovery protocols.
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Protocol

Reconstitution & Usage Protocol

Important: Only chill the water 3 minutes before reconstituting the peptide. Do not prepare with very cold water, as it can freeze, lose effect or be damaged.
1Reconstitution
Materials: 1 vial of Ipamorelin 10 mg · 1 vial of bacteriostatic water · U-100 insulin syringe · alcohol wipes.
  1. Bring the vial to room temperature for 10–15 minutes.
  2. Disinfect the rubber caps with an alcohol wipe.
  3. Draw 2 mL of bacteriostatic water (200 IU in an insulin syringe).
  4. Inject the water slowly down the inner wall of the vial.
  5. Do not shake. Swirl gently until the solution is clear.
Label with the date and refrigerate (2–8 °C). Stable for 28 days.
2Concentration & Dosing
Reconstituting 10 mg in 2 mL → 5 mg/mL = 50 mcg per IU.
Target doseUnitsVolume
500 mcg (standard)10 IU0.10 mL
Universal formula: IU = (dose in mcg ÷ 50)
3Application
Route
Subcutaneous in the abdomen.
Frequency
1–3 times a day (morning fasted, pre-workout, before sleep).
Cycle
8–16 weeks. Classic stack with CJC-1295 No DAC for a synergistic effect.
  • Fasted: no food 2 h before or 30 min after so as not to block the GH pulse.
  • Before applying: let the drawn dose lose its chill (only the amount to be injected) — hold the syringe in your hand for 2–3 minutes.
  • After applying: gently massage the area for ~40 seconds to disperse the peptide and improve absorption.
Importante: Solo poner a enfriar el agua 3 minutos antes de reconstituir el péptido. No preparar con agua muy fría, porque se puede congelar, perder efecto o dañarse.
1Reconstitución
Materiales: 1 vial de Ipamorelin 10 mg · 1 vial de agua bacteriostática · jeringa de insulina U-100 · toallitas de alcohol.
  1. Atemperar el vial 10–15 minutos.
  2. Desinfectar las tapas de goma con toallita de alcohol.
  3. Cargar 2 mL de agua bacteriostática (200 UI en jeringa de insulina).
  4. Inyectar el agua lentamente por la pared interior del vial.
  5. No agitar. Girar suavemente hasta solución transparente.
Etiquetar con fecha y refrigerar (2–8 °C). Estable 28 días.
2Concentración y dosis
Reconstituyendo 10 mg en 2 mL → 5 mg/mL = 50 mcg por UI.
Dosis objetivoUnidadesVolumen
500 mcg (estándar)10 UI0,10 mL
Fórmula universal: UI = (dosis en mcg ÷ 50)
3Aplicación
Vía
Subcutánea en abdomen.
Frecuencia
1–3 veces al día (mañana en ayunas, pre-entreno, antes de dormir).
Ciclo
8–16 semanas. Stackeo clásico con CJC-1295 No DAC para efecto sinérgico.
  • En ayunas: sin alimentos 2 h antes ni 30 min después para no bloquear el pulso de GH.
  • Antes de aplicar: dejar que la dosis cargada pierda el frío (solo la cantidad a inyectar) — sostener la jeringa en la mano 2–3 minutos.
  • Después de aplicar: masaje suave en la zona durante ~40 segundos para dispersar el péptido y mejorar absorción.
Important : Ne mettre l'eau à refroidir que 3 minutes avant de reconstituer le peptide. Ne pas préparer avec de l'eau très froide, car elle peut geler, perdre son effet ou être endommagée.
1Reconstitution
Matériel : 1 flacon d'Ipamorelin 10 mg · 1 flacon d'eau bactériostatique · seringue à insuline U-100 · lingettes alcoolisées.
  1. Laisser le flacon revenir à température ambiante pendant 10–15 minutes.
  2. Désinfecter les bouchons en caoutchouc avec une lingette alcoolisée.
  3. Prélever 2 mL d'eau bactériostatique (200 UI dans une seringue à insuline).
  4. Injecter l'eau lentement le long de la paroi intérieure du flacon.
  5. Ne pas agiter. Faire tourner doucement jusqu'à obtenir une solution transparente.
Étiqueter avec la date et réfrigérer (2–8 °C). Stable pendant 28 jours.
2Concentration et dosage
En reconstituant 10 mg dans 2 mL → 5 mg/mL = 50 mcg par UI.
Dose cibleUnitésVolume
500 mcg (standard)10 UI0,10 mL
Formule universelle : UI = (dose en mcg ÷ 50)
3Application
Voie
Sous-cutanée dans l'abdomen.
Fréquence
1–3 fois par jour (le matin à jeun, avant l'entraînement, avant de dormir).
Cycle
8–16 semaines. Stack classique avec le CJC-1295 No DAC pour un effet synergique.
  • À jeun : aucun aliment 2 h avant ni 30 min après afin de ne pas bloquer le pulse de GH.
  • Avant d'appliquer : laisser la dose prélevée perdre son froid (uniquement la quantité à injecter) — tenir la seringue dans la main pendant 2–3 minutes.
  • Après l'application : masser doucement la zone pendant ~40 secondes pour disperser le peptide et améliorer l'absorption.

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Research Highlights

Research Highlights

FAQ

Frequently Asked Questions

Why is Ipamorelin considered the most selective GH secretagogue?

In research models, Ipamorelin stimulates a physiological GH pulse without the notable rises in cortisol, prolactin or appetite seen with GHRP-6 or GHRP-2, which is why it is described as the 'cleanest' compound of its class. This selectivity makes it of interest for studies on prolonged-use protocols. For research use only.

How is Ipamorelin 10 mg reconstituted in research settings?

The 10 mg vial is reconstituted with 2 mL of bacteriostatic water, giving a concentration of 5 mg/mL, or 50 mcg per IU on a U-100 insulin syringe. A standard 500 mcg dose corresponds to 10 IU (0.10 mL). The solution is labeled, refrigerated at 2–8 °C and remains stable for 28 days. For research use only.

Why is Ipamorelin often paired with CJC-1295 No DAC?

Ipamorelin (a GH secretagogue) and CJC-1295 No DAC (a GHRH analog) act on complementary pathways, so research protocols frequently combine them for a synergistic effect on the GH pulse. This classic stack is studied over cycles of 8–16 weeks. For research use only.

Why does timing relative to food matter for Ipamorelin?

Research protocols administer Ipamorelin in a fasted state, with no food 2 hours before or 30 minutes after, because elevated blood glucose and insulin can blunt the GH pulse. Common timing windows are morning fasted, pre-workout and before sleep. For research use only.

Related Compounds

Related Compounds

CJC-1295 No DAC Growth Hormone
CJC-1295 No DAC

CJC-1295 No DAC (without Drug Affinity Complex), also called Modified GRF 1-29, is a synthetic analog of growth hormone-releasing hormone (GHRH) with a short half-life (~30 minutes). This generates a physiological GH pulse similar to the natural one, without sustained elevations that could desensitize the pituitary. It is almost always combined with a GHRP (Ipamorelin or GHRP-6) for a synergistic effect 5–10 times greater than either one alone.

99% Purity
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Tesamorelin Growth Hormone
Tesamorelin

Tesamorelin is a synthetic GHRH analog approved by the FDA for the treatment of HIV-associated lipodystrophy, known for its efficacy in reducing abdominal visceral fat. It stimulates the pituitary to release GH in a pulsatile manner, with potency superior to CJC-1295. It is the only secretagogue with robust clinical evidence for visceral fat reduction and improvement of hepatic markers in non-alcoholic fatty liver disease.

99% Purity
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GHRP-6 Growth Hormone
GHRP-6

GHRP-6 (Growth Hormone Releasing Peptide-6) is a hexamer peptide that stimulates the pulsatile release of growth hormone (GH) from the pituitary gland by activating the ghrelin receptor. Unlike other GHRPs, GHRP-6 produces a pronounced secondary effect: a significant increase in appetite, which makes it a useful option for athletes in a muscle-gain (bulking) phase or for individuals who struggle to raise their caloric intake.

99% Purity
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