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CJC-1295 No DAC

CJC-1295 No DAC

11
GHRH analog · Pulsatile growth
99% Purity Growth Hormone

CJC-1295 No DAC (without Drug Affinity Complex), also called Modified GRF 1-29, is a synthetic analog of growth hormone-releasing hormone (GHRH) with a short half-life (~30 minutes). This generates a physiological GH pulse similar to the natural one, without sustained elevations that could desensitize the pituitary. It is almost always combined with a GHRP (Ipamorelin or GHRP-6) for a synergistic effect 5–10 times greater than either one alone.

Key Benefits
Physiological GH pulse
Stacks perfectly with Ipamorelin
Improves body composition
Optimizes deep sleep
Accelerates recovery
Anti-aging effect
Mechanism of Action
As a synthetic GHRH analog with a short half-life (~30 minutes), it binds the pituitary GHRH receptors and triggers a physiological GH pulse similar to the natural one, without sustained elevations that desensitize the gland. Combined with a GHRP (Ipamorelin or GHRP-6) it produces a synergistic effect 5–10 times greater than either one alone.
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Protocol

Reconstitution & Usage Protocol

Important: Only chill the water for 3 minutes before reconstituting the peptide. Do not prepare it with very cold water, because it can freeze, lose effect or be damaged.
1Reconstitution
Materials: 1 vial of CJC-1295 No DAC 5 mg · 1 vial of bacteriostatic water · U-100 insulin syringe · alcohol wipes.
  1. Let the vial reach room temperature for 10–15 minutes.
  2. Disinfect the rubber caps with an alcohol wipe.
  3. Draw 2 mL of bacteriostatic water (200 IU on an insulin syringe).
  4. Inject the water slowly down the inner wall of the vial.
  5. Do not shake. Swirl gently until the solution is clear.
Label with the date and refrigerate (2–8 °C). Stable for 28 days.
2Concentration & Dosing
Reconstituting 5 mg in 2 mL → 2.5 mg/mL = 25 mcg per IU.
Target doseUnitsVolume
100 mcg (low)4 IU0.04 mL
200 mcg (standard)8 IU0.08 mL
300 mcg (high)12 IU0.12 mL
Universal formula: IU = (dose in mcg ÷ 25)
3Application
Route
Subcutaneous in the abdomen.
Frequency
1–3 times a day (morning, pre-workout, before sleep).
Cycle
8–16 weeks. Fasted 2 h before and 30 min after application.
  • Combine with Ipamorelin in the same syringe for GHRH + GHRP synergy.
  • Before applying: let the drawn dose lose its chill (only the amount to be injected) — hold the syringe in your hand for 2–3 minutes.
  • After applying: gently massage the area for ~40 seconds to disperse the peptide and improve absorption.
Importante: Solo poner a enfriar el agua 3 minutos antes de reconstituir el péptido. No preparar con agua muy fría, porque se puede congelar, perder efecto o dañarse.
1Reconstitución
Materiales: 1 vial de CJC-1295 No DAC 5 mg · 1 vial de agua bacteriostática · jeringa de insulina U-100 · toallitas de alcohol.
  1. Atemperar el vial 10–15 minutos.
  2. Desinfectar las tapas de goma con toallita de alcohol.
  3. Cargar 2 mL de agua bacteriostática (200 UI en jeringa de insulina).
  4. Inyectar el agua lentamente por la pared interior del vial.
  5. No agitar. Girar suavemente hasta solución transparente.
Etiquetar con fecha y refrigerar (2–8 °C). Estable 28 días.
2Concentración y dosis
Reconstituyendo 5 mg en 2 mL → 2,5 mg/mL = 25 mcg por UI.
Dosis objetivoUnidadesVolumen
100 mcg (baja)4 UI0,04 mL
200 mcg (estándar)8 UI0,08 mL
300 mcg (alta)12 UI0,12 mL
Fórmula universal: UI = (dosis en mcg ÷ 25)
3Aplicación
Vía
Subcutánea en abdomen.
Frecuencia
1–3 veces al día (mañana, pre-entreno, antes de dormir).
Ciclo
8–16 semanas. En ayunas 2 h antes y 30 min después de la aplicación.
  • Combinar con Ipamorelin en la misma jeringa para sinergia GHRH + GHRP.
  • Antes de aplicar: dejar que la dosis cargada pierda el frío (solo la cantidad a inyectar) — sostener la jeringa en la mano 2–3 minutos.
  • Después de aplicar: masaje suave en la zona durante ~40 segundos para dispersar el péptido y mejorar absorción.
Important : mettre l'eau à refroidir seulement 3 minutes avant de reconstituer le peptide. Ne pas préparer avec de l'eau très froide, car il peut geler, perdre son effet ou s'abîmer.
1Reconstitution
Matériel : 1 flacon de CJC-1295 No DAC 5 mg · 1 flacon d'eau bactériostatique · seringue à insuline U-100 · lingettes d'alcool.
  1. Laisser le flacon revenir à température ambiante pendant 10 à 15 minutes.
  2. Désinfecter les bouchons en caoutchouc avec une lingette d'alcool.
  3. Prélever 2 mL d'eau bactériostatique (200 UI sur une seringue à insuline).
  4. Injecter l'eau lentement le long de la paroi interne du flacon.
  5. Ne pas agiter. Faire tournoyer doucement jusqu'à obtenir une solution transparente.
Étiqueter avec la date et réfrigérer (2 à 8 °C). Stable 28 jours.
2Concentration et dosage
En reconstituant 5 mg dans 2 mL → 2,5 mg/mL = 25 mcg par UI.
Dose cibleUnitésVolume
100 mcg (basse)4 UI0,04 mL
200 mcg (standard)8 UI0,08 mL
300 mcg (haute)12 UI0,12 mL
Formule universelle : UI = (dose en mcg ÷ 25)
3Application
Voie
Sous-cutanée dans l'abdomen.
Fréquence
1 à 3 fois par jour (matin, avant l'entraînement, avant le coucher).
Cycle
8 à 16 semaines. À jeun 2 h avant et 30 min après l'application.
  • Combiner avec l'Ipamorelin dans la même seringue pour une synergie GHRH + GHRP.
  • Avant l'application : laisser la dose prélevée perdre son froid (seulement la quantité à injecter) — tenir la seringue dans la main 2 à 3 minutes.
  • Après l'application : masser doucement la zone pendant ~40 secondes pour disperser le peptide et améliorer l'absorption.

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Research Highlights

Research Highlights

FAQ

Frequently Asked Questions

What is CJC-1295 No DAC and how does it work in research models?

CJC-1295 No DAC (Modified GRF 1-29) is a synthetic GHRH analog studied for its ability to trigger a physiological, pulsatile GH release. Because its half-life is only about 30 minutes, research models show a natural GH pulse rather than the sustained elevation that can desensitize the pituitary.

How does the No DAC version differ from CJC-1295 with DAC?

The No DAC form lacks the Drug Affinity Complex, so it has a short ~30 minute half-life and preserves the body's physiological GH pulse pattern. The DAC version binds albumin and stays in circulation for days, producing a sustained GH bleed rather than discrete pulses, which makes the two forms suited to different research questions.

Why is it so often combined with a GHRP like Ipamorelin?

In research models CJC-1295 No DAC is almost always paired with a GHRP (Ipamorelin or GHRP-6) because the GHRH-plus-secretagogue combination produces a synergistic effect reported as 5–10 times greater than either compound alone. The two can be drawn into the same syringe to study this GHRH + GHRP synergy.

How is the 5 mg vial reconstituted and what concentration does it give?

Reconstituting 5 mg in 2 mL of bacteriostatic water yields 2.5 mg/mL, equal to 25 mcg per IU on a U-100 insulin syringe. A 100 mcg dose is 4 IU (0.04 mL), 200 mcg is 8 IU (0.08 mL) and 300 mcg is 12 IU (0.12 mL). Once prepared, label with the date, refrigerate at 2–8 °C and the solution stays stable for 28 days.

Related Compounds

Related Compounds

Ipamorelin Growth Hormone
Ipamorelin

Ipamorelin is a GH secretagogue pentapeptide considered the most selective and 'cleanest' of its class. Unlike GHRP-6 or GHRP-2, it does not cause a notable rise in cortisol, prolactin or appetite, making it the preferred option for anti-aging, fat-loss and recovery protocols without hormonal side effects. It generates a physiological GH pulse similar to the natural one, ideal for prolonged use.

99% Purity
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Tesamorelin Growth Hormone
Tesamorelin

Tesamorelin is a synthetic GHRH analog approved by the FDA for the treatment of HIV-associated lipodystrophy, known for its efficacy in reducing abdominal visceral fat. It stimulates the pituitary to release GH in a pulsatile manner, with potency superior to CJC-1295. It is the only secretagogue with robust clinical evidence for visceral fat reduction and improvement of hepatic markers in non-alcoholic fatty liver disease.

99% Purity
Details →
GHRP-6 Growth Hormone
GHRP-6

GHRP-6 (Growth Hormone Releasing Peptide-6) is a hexamer peptide that stimulates the pulsatile release of growth hormone (GH) from the pituitary gland by activating the ghrelin receptor. Unlike other GHRPs, GHRP-6 produces a pronounced secondary effect: a significant increase in appetite, which makes it a useful option for athletes in a muscle-gain (bulking) phase or for individuals who struggle to raise their caloric intake.

99% Purity
Details →

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