HCG 5000 IU

Testicular axis restoration · LH mimetic

99% Purity Hormonal Flagship

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone that mimics the action of luteinizing hormone (LH), directly stimulating testicular Leydig cells to produce endogenous testosterone. It is used in male fertility protocols, recovery of the HPG axis after steroid cycles (PCT), and maintenance of testicular volume in hormone replacement therapy (TRT). In women it is used for ovulation induction.

Key Benefits

Reactivates endogenous testosterone production

Prevents testicular atrophy

Preserves fertility on TRT

Key tool in post-cycle PCT

Induces ovulation in fertility protocols

Maintains libido and sexual function

Mechanism of Action

HCG acts as a luteinizing hormone (LH) mimetic, binding to its receptors and directly stimulating testicular Leydig cells to reactivate endogenous testosterone production. Through this pathway it restores the suppressed HPG axis and preserves testicular volume and sperm function.

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Protocol

Reconstitution & Usage Protocol

Important: Only chill the water 3 minutes before reconstituting the peptide. Do not prepare with very cold water, because it may freeze, lose effect, or be damaged.

1Reconstitution

Materials: 1 vial of lyophilized HCG 5000 IU · 1 vial of bacteriostatic water · U-100 insulin syringe · alcohol wipes.

Bring the vial to room temperature for 10–15 minutes.
Disinfect the caps of both vials with an alcohol wipe.
Draw up 3 mL of bacteriostatic water with a 3 mL syringe, or in 2 successive draws with an insulin syringe.
Inject the water slowly down the wall of the HCG vial. It is a fragile peptide; avoid a direct stream.
Do not shake. Swirl gently between the palms for 30 seconds until the solution is clear.

Label with the date and refrigerate immediately (2–8 °C). Stable 30 days once reconstituted.

2Concentration & Dosing

Reconstituting 5000 IU in 3 mL → 1666 IU/mL ≈ 16.66 IU per syringe unit.

Target dose	Units	Volume
250 IU	15 IU	0.15 mL
500 IU (standard)	30 IU	0.30 mL
1000 IU	60 IU	0.60 mL
1500 IU (high)	90 IU	0.90 mL

Universal formula: syringe IU = desired dose ÷ 16.66

3Application

Route

Subcutaneous in the abdomen or intramuscular (glute/thigh).

Frequency

2–3 times per week for maintenance; daily in fertility protocols.

Cycle

TRT protocol: 250–500 IU every 3 days alongside testosterone. PCT protocol: 500–1000 IU every 2 days for 3–4 weeks.

Before applying: let the drawn-up dose lose its chill (only the amount to be injected) — hold the syringe in your hand for 2–3 minutes.
After applying: gentle massage of the area for ~40 seconds to disperse the peptide and improve absorption.

Importante: Solo poner a enfriar el agua 3 minutos antes de reconstituir el péptido. No preparar con agua muy fría, porque se puede congelar, perder efecto o dañarse.

1Reconstitución

Materiales: 1 vial de HCG 5000 UI liofilizado · 1 vial de agua bacteriostática · jeringa de insulina U-100 · toallitas de alcohol.

Atemperar el vial a temperatura ambiente 10–15 minutos.
Desinfectar las tapas de ambos viales con toallita de alcohol.
Cargar 3 mL de agua bacteriostática con jeringa de 3 mL, o en 2 cargas sucesivas con jeringa de insulina.
Inyectar el agua lentamente por la pared del vial de HCG. Es un péptido frágil, evitar chorro directo.
No agitar. Girar suavemente entre las palmas durante 30 segundos hasta solución transparente.

Etiquetar con fecha y refrigerar inmediatamente (2–8 °C). Estable 30 días reconstituido.

2Concentración y dosis

Reconstituyendo 5000 UI en 3 mL → 1666 UI/mL ≈ 16,66 UI por unidad de jeringa.

Dosis objetivo	Unidades	Volumen
250 UI	15 UI	0,15 mL
500 UI (estándar)	30 UI	0,30 mL
1000 UI	60 UI	0,60 mL
1500 UI (alta)	90 UI	0,90 mL

Fórmula universal: UI de jeringa = dosis deseada ÷ 16,66

3Aplicación

Vía

Subcutánea en abdomen o intramuscular (glúteo/muslo).

Frecuencia

2–3 veces por semana para mantenimiento; diaria en protocolos de fertilidad.

Ciclo

Protocolo en TRT: 250–500 UI cada 3 días junto con testosterona. Protocolo PCT: 500–1000 UI cada 2 días durante 3–4 semanas.

Antes de aplicar: dejar que la dosis cargada pierda el frío (solo la cantidad a inyectar) — sostener la jeringa en la mano 2–3 minutos.
Después de aplicar: masaje suave en la zona durante ~40 segundos para dispersar el péptido y mejorar absorción.

Important : Ne mettre l'eau à refroidir que 3 minutes avant de reconstituer le peptide. Ne pas préparer avec une eau très froide, car elle peut geler, perdre son effet ou s'abîmer.

1Reconstitution

Matériel : 1 flacon de HCG 5000 UI lyophilisé · 1 flacon d'eau bactériostatique · seringue à insuline U-100 · lingettes d'alcool.

Ramener le flacon à température ambiante pendant 10–15 minutes.
Désinfecter les bouchons des deux flacons avec une lingette d'alcool.
Prélever 3 mL d'eau bactériostatique avec une seringue de 3 mL, ou en 2 prélèvements successifs avec une seringue à insuline.
Injecter l'eau lentement le long de la paroi du flacon de HCG. C'est un peptide fragile, éviter le jet direct.
Ne pas agiter. Faire tourner doucement entre les paumes pendant 30 secondes jusqu'à obtenir une solution transparente.

Étiqueter avec la date et réfrigérer immédiatement (2–8 °C). Stable 30 jours une fois reconstitué.

2Concentration et dosage

En reconstituant 5000 UI dans 3 mL → 1666 UI/mL ≈ 16,66 UI par unité de seringue.

Dose cible	Unités	Volume
250 UI	15 UI	0,15 mL
500 UI (standard)	30 UI	0,30 mL
1000 UI	60 UI	0,60 mL
1500 UI (élevée)	90 UI	0,90 mL

Formule universelle : UI de seringue = dose souhaitée ÷ 16,66

3Application

Voie

Sous-cutanée dans l'abdomen ou intramusculaire (fessier/cuisse).

Fréquence

2–3 fois par semaine pour l'entretien ; quotidienne dans les protocoles de fertilité.

Cycle

Protocole en TRT : 250–500 UI tous les 3 jours avec la testostérone. Protocole PCT : 500–1000 UI tous les 2 jours pendant 3–4 semaines.

Avant l'application : laisser la dose prélevée perdre son froid (uniquement la quantité à injecter) — tenir la seringue dans la main 2–3 minutes.
Après l'application : massage doux de la zone pendant ~40 secondes pour disperser le peptide et améliorer l'absorption.

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Research Highlights

Research models report that HCG, by mimicking LH and binding Leydig-cell receptors, directly stimulates endogenous testosterone production independently of pituitary signaling.
Study data associate HCG co-administration with preservation of testicular volume and spermatogenesis during exogenous testosterone exposure that otherwise suppresses the HPG axis.
In post-cycle (PCT) research frameworks, HCG is reported to accelerate reactivation of the suppressed gonadal axis and is also evaluated for ovulation induction in female models.

FAQ

Frequently Asked Questions

What is HCG and how does it act as an LH mimetic in research models?

HCG is a glycoprotein hormone whose beta subunit closely resembles luteinizing hormone (LH), allowing it to bind LH receptors and directly stimulate testicular Leydig cells to produce endogenous testosterone. In research models this LH-mimetic action is studied for reactivating a suppressed HPG axis. It is supplied strictly for in-vitro and laboratory use.

Why is HCG studied alongside testosterone in TRT and PCT research?

Exogenous testosterone suppresses the HPG axis and can lead to testicular atrophy and reduced spermatogenesis in study models. HCG is examined because, by directly stimulating the testes, it is reported to preserve testicular volume and fertility during TRT and to help reactivate endogenous production in post-cycle (PCT) frameworks. These figures describe the literature only and are not human-use instructions.

What concentration and dosing figures result from reconstituting HCG 5000 IU?

Reconstituting 5000 IU in 3 mL of bacteriostatic water yields 1666 IU/mL, equal to roughly 16.66 IU per syringe unit. Reference draws in the literature include 250 IU (15 units / 0.15 mL), 500 IU (30 units / 0.30 mL), 1000 IU (60 units / 0.60 mL) and 1500 IU (90 units / 0.90 mL). The universal conversion is syringe IU = desired dose ÷ 16.66; these are laboratory measurement parameters only.

How should reconstituted HCG be stored and handled in the lab?

HCG is a fragile peptide: chill the bacteriostatic water only 3 minutes before reconstitution, inject it slowly down the vial wall, and swirl gently for 30 seconds rather than shaking. Label with the date and refrigerate immediately at 2-8 °C, where the reconstituted solution remains stable for 30 days under aseptic technique. This material is for laboratory research use only and not for human or veterinary use.

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