SARM

Selective Androgen Receptor Modulators (SARMs):

SARMs are a class of therapeutic compounds that have similar properties to anabolic agents, but with reduced androgenic properties. This property allows SARMs the advantage of androgen-receptor specificity, tissue selectivity, and the potential for fewer side effects compared to traditional anabolic androgenic steroids (AAS). They are intended to have the same kind of effects as androgenic drugs like anabolic steroids but being more selective in their action allowing them to be used in more fields than the known legit uses of anabolic steroids.

Ligandrol (LGD-4033)

Ligandrol, technically known as LGD-4033,actually is one of the most popular SARMs on the market. Developed by Ligand Pharmaceuticals, hence the name Ligandrol, it is often marketed under the name LGD-4033. Ligandrol is famous for its role in muscle growth and bone strengthening. It binds to the androgen receptor with high affinity and selectivity, demonstrating anabolic activity in muscles and anti-resorptive and anabolic activity in bones. This makes it a potential therapeutic option for treating conditions like muscle wasting and osteoporosis. Its benefits include increased muscle mass, improved strength, and potential assistance in healing and recovery processes. However, it’s important to note that while SARMs like Ligandrol show promise, they are still under investigation and are not approved by regulatory agencies like the FDA for clinical use.

Andarine S-23

Andarine S-23, technically known as S-23, Andarine is a potent investigational SARM known for its unique ability to promote muscle mass, reduce body fat, and potentially increase bone density. Developed for the treatment of conditions like muscle mass lost and osteoporosis, S-23 binds selectively the androgen receptors in skeletal muscle and bone tissue. This selective binding is key to its anabolic effects without the full range of androgenic side effects, typically associated with anabolic steroids. Additionally, S-23 has earned interest for its potential role in male hormonal contraception due to its ability to suppress natural testosterone production.

Cardarine

Cardarine, technically known as GW-501516, Cardarine is often mistakenly categorized as a SARM, but it is actually a Peroxisome Proliferator-Activated Receptor delta (PPARδ) agonist. This compound was initially developed for its potential benefits in treating metabolic and cardiovascular diseases. Cardarine works by activating PPARδ, a receptor that plays a crucial role in energy metabolism. By doing so, it enhances endurance, fat burning, and muscle recovery. Its ability to increase fatty acid oxidation in skeletal muscle makes it a compound of interest for athletes and bodybuilders seeking to improve performance and physique.

Ibutamoren

Ibutamoren technically known as MK-677, Ibutamoren is often grouped with SARMs, but it is actually a selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has gained significant attention in the fields of muscle building and fitness due to its ability to significantly increase levels of growth hormone and insulin-like growth factor 1 (IGF-1) without affecting cortisol levels.

Ibutamoren is primarily researched for its potential in treating conditions like growth hormone deficiency, muscle mass lost, and osteoporosis. Its ability to stimulate GH production means it could aid in muscle growth, increase bone density, and improve sleep quality and overall longevity.

Testolone

Testolone. technically known as RAD-140, Testolone is one of the newer SARMs that has gained popularity in the fitness and bodybuilding communities. It is designed to provide the anabolic effects of testosterone without the adverse effects typically associated with anabolic steroids.

Testolone’s primary mechanism of action involves selectively targeting and activating androgen receptors in muscle and bone tissues, which leads to enhanced muscle growth and bone density. This selectivity also means that it has a lower probability of causing the unwanted side effects that are common with steroids, such as liver toxicity or estrogen-related side effects. RAD-140 is particularly noted for its neuroprotective properties. It is believed to offer protection against neurodegenerative diseases due to its ability to combat androgen receptor-related neurodegenerative processes. This makes it a compound of interest not only for athletes and bodybuilders but also for potential therapeutic applications in neurodegenerative diseases.

Ostarine

Ostarine technically known as MK-2866 or Enobosarm, Ostarine is one of the most well-known and researched SARMs. Initially developed for its potential in treating conditions such as muscle mass lost and osteoporosis, Ostarine selectively binds the androgen receptors in muscle and bone tissues. This selective action promotes anabolic activity, leading to increased muscle mass and strength, as well as bone health, without the significant androgenic side effects often associated with anabolic steroids.

Ostarine has earned attention in the fitness community for its potential to enhance physical performance and muscle recovery. Its ability to stimulate muscle growth while potentially reducing body fat makes it a compound of interest for athletes and bodybuilders.

Myostine

MYOSTINE YK-11. YK-11, often referred to it by its commercial name MYOSTINE, stands out in the SARM category due to its unique structure and function. Unlike typical SARMs, YK-11 is a synthetic steroidal SARM, which means it has a structure more similar to anabolic steroids. It is known for its potent ability to act as a myostatin inhibitor. Myostatin is a protein that inhibits muscle growth, and by inhibiting myostatin, YK-11 is theorized to significantly enhance muscle growth and strength.

YK-11 is also believed to promote the growth of new muscle fibers, potentially leading bigger muscle growth than traditional SARMs. This has made it a compound of interest in the bodybuilding community for its potential to dramatically enhance muscle building.